Dino

Paromomycin Sulfate

Paromomycin Sulfate

Synonyms Paromomycin sulfate salt

CAS Number: 1263-89-4 Molecular Formula: C23H45N5O14·×H2SO4·×H2O Molecular Weight: 713.706 g/mol

Beilstein Registry Number: 5715182 EC Number: 215-031-7 MDL Number: MFCD00079278

Configure Your Product:

SKU 02156056-CF
Price:
$72.80
In Stock
Request a quote
Description

Product Description

Paromomycin Sulfate

Application Notes

Paromomycin is a broad spectrum aminoglycoside antibiotic produced by Streptomyces rimosus var. paromomycinus. It has in vitro and in vivo activity similar to neomycin. It is effective against Gram-negative bacteria, Gram-positive bacteria, some protozoan species, and limited antihelminth.It is used to study bacterial protein synthesis at the level of 16S ribosomal RNA and 30S ribosome assembly. Paromomycin is used to study cytosine-cytosine (CC) mismatch-containing RNA molecules and is used to inhibit Cryptosporidium infection of a human enterocyte cell line.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Antibiotic

Specifications
SKU 02156056-CF
Application Notes Paromomycin is a broad spectrum aminoglycoside antibiotic produced by Streptomyces rimosus var. paromomycinus. It has in vitro and in vivo activity similar to neomycin. It is effective against Gram-negative bacteria, Gram-positive bacteria, some protozoan species, and limited antihelminth.It is used to study bacterial protein synthesis at the level of 16S ribosomal RNA and 30S ribosome assembly. Paromomycin is used to study cytosine-cytosine (CC) mismatch-containing RNA molecules and is used to inhibit Cryptosporidium infection of a human enterocyte cell line.
Beilstein Registry Number 5715182
Biochemical Physiological Actions Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.
EC Number 215-031-7
Format powder
Applications Antibiotic
Molecular Formula C23H45N5O14·×H2SO4·×H2O
Molecular Weight 713.706 g/mol
Physical Appearance White Powder
Potency >675 µg/mg
Product Families Description Paromomycin sulfate
Product Overview Paromomycin Sulfate
Purity >97%
RTECS Number WK2320000
Storage and Handling Store at Room Temperature (15-30 °C).
Typical Working Concentration 100 mg/L
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.