Metronidazole

Metronidazole

Synonyms 2-Methyl-5-nitroimidazole-1-ethanol; 1-(2-Hydroxyethyl)-2-methyl-5-nitroimidazole; 1-(b-Ethylol)-2-methyl-5-nitro-3-azapyrrole

CAS Number: 443-48-1 Molecular Formula: C6H9N3O3 Molecular Weight: 171.156 g/mol

Beilstein Registry Number: 611683 EC Number: 207-136-1 MDL Number: MFCD00009750

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SKU 02155710-CF
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Description

Product Description

Metronidazole

Application Notes

Metronidazole suppress protozoans such as Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis. Further studies show that Metronidazole has been used to repress the growth of gram-negative anaerobes belonging to the Bacteroides and Fusobacterium, and gram-positive anaerobes such as peptostreptococcus and Clostridia. The advantages of this antibiotic is that it affects a high percentage of gram-negative bacteria and has greater tissue penetration. Furthermore, the gene hefA codes for the TolC efflux pump in Helicobacter pylori which is resistant to Metronidazole.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Antibiotics||Chromatography||Antibacterial

Specifications
SKU 02155710-CF
Alternate Names 2-Methyl-5-nitroimidazole-1-ethanol; 1-(2-Hydroxyethyl)-2-methyl-5-nitroimidazole; 1-(b-Ethylol)-2-methyl-5-nitro-3-azapyrrole
Application Notes Metronidazole suppress protozoans such as Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis. Further studies show that Metronidazole has been used to repress the growth of gram-negative anaerobes belonging to the Bacteroides and Fusobacterium, and gram-positive anaerobes such as peptostreptococcus and Clostridia. The advantages of this antibiotic is that it affects a high percentage of gram-negative bacteria and has greater tissue penetration. Furthermore, the gene hefA codes for the TolC efflux pump in Helicobacter pylori which is resistant to Metronidazole.
Beilstein Registry Number 611683
EC Number 207-136-1
Format powder
Hazard Statements H351
Applications Antibiotics||Chromatography||Antibacterial
Loss on Drying ≤2%
MDL # MFCD00009750
Melting Point 316 to 320° F (NTP, 1992)
Molecular Formula C6H9N3O3
Molecular Weight 171.156 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Gloves
pH pH of saturated aq soln is 5.8
Physical Appearance White Powder
Product Families Description Metronidazole
Product Overview Metronidazole
RTECS Number NI5600000
Safety Symbol GHS08
Solubility >25.7 [ug/mL]
Storage and Handling Store at +4 °C.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Vapor Pressure 3.1X10-7 mm Hg at 25 deg C (est)