Bupivacaine Hydrochloride

Bupivacaine Hydrochloride

Synonyms 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide

CAS Number: 14252-80-3 Molecular Formula: C18H28N2O · HCl Molecular Weight: 324.893 g/mol

EC Number: 241-917-8 MDL Number: MFCD00078956

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SKU 02154904-CF
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Description

Product Description

Bupivacaine Hydrochloride

Application Notes

Bupivacaine is used as a long-acting local anesthetic. It is used mainly for infiltration and regional nerveblocks, but is not recommended for topical anesthesia.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Local anesthetic

Specifications
SKU 02154904-CF
Alternate Names 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
Application Notes Bupivacaine is used as a long-acting local anesthetic. It is used mainly for infiltration and regional nerveblocks, but is not recommended for topical anesthesia.
Biochemical Physiological Actions Bupivacaine is a sodium channel blocker, local anesthetic. It binds to the intracellular portion of sodium channels and blocks sodium influx into nerve cells, which prevents depolarization. Since pain transmitting nerve fibres tend to be thinner and either unmyelinated or lightly myelinated, the agent can diffuse more readily into them than into thicker and more heavily myelinated nerve fibres like touch, proprioception, etc. (Myelin is non-polar / lipophilic). It should be noted, however, that bupivacaine also blocks specific potassium channels, an effect contributing to resting membrane potential depolarization.
EC Number 241-917-8
Hazard Statements H300-H310-H330
Applications Local anesthetic
MDL # MFCD00078956
Molecular Formula C18H28N2O · HCl
Molecular Weight 324.893 g/mol
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator cartridge, respirator filter
Physical Appearance White Powder
Product Families Description Bupivacaine
Product Overview Bupivacaine Hydrochloride
RTECS Number TK6125000
Safety Symbol GHS06
Storage and Handling Store at Room Temperature (15-30 °C).
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.