Acetic Anhydride

Acetic Anhydride

Synonyms Acetic Acid Anhydride; Acetic Oxide; Acetyl Anhydride; Anhydride Acetique; Acetyl oxide

CAS Number: 108-24-7 Molecular Formula: C4H6O3 Molecular Weight: 102.089 g/mol

Beilstein Registry Number: 385737 EC Number: 203-564-8 MDL Number: MFCD00008705

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SKU 02154680-CF
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Description

Product Description

Acetic Anhydride

Application Notes

Acetic anhydride is a reagent that is used in the manufacturing of acetyl compounds and cellulose acetates. It is also utilized as a solvent in the examination of wool fat, glycerol, fatty and volatile oils, and resins. In the synthesis of organic compounds, acetic anhydride is used in various reactions, including the cleavage of dialkyl ethers, the formation of anhydrides from carboxylic acids, the addition of methylthiomethyl groups to phenol rings, and the addition of acyl and acyloxy groups across double bonds. Acetic anhydride has been used to hyperacetylate histones to investigate transcriptional effects of the NAD-dependent histone deacetylase Sir2 in Drosophila on a complex of the hyperacetylated histones with DNA. Acetic anhydride is utilized in an assay of a fluorescently labeled peptide catalyst library for application to the resolution of secondary alcohols.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Reagent||Solvent

Specifications
SKU 02154680-CF
Alternate Names Acetic Acid Anhydride; Acetic Oxide; Acetyl Anhydride; Anhydride Acetique; Acetyl oxide
Application Notes Acetic anhydride is a reagent that is used in the manufacturing of acetyl compounds and cellulose acetates. It is also utilized as a solvent in the examination of wool fat, glycerol, fatty and volatile oils, and resins. In the synthesis of organic compounds, acetic anhydride is used in various reactions, including the cleavage of dialkyl ethers, the formation of anhydrides from carboxylic acids, the addition of methylthiomethyl groups to phenol rings, and the addition of acyl and acyloxy groups across double bonds. Acetic anhydride has been used to hyperacetylate histones to investigate transcriptional effects of the NAD-dependent histone deacetylase Sir2 in Drosophila on a complex of the hyperacetylated histones with DNA. Acetic anhydride is utilized in an assay of a fluorescently labeled peptide catalyst library for application to the resolution of secondary alcohols.
Auto Ignition 626° F (USCG, 1999)
Beilstein Registry Number 385737
Boiling Point 283.19° F at 760 mm Hg (NTP, 1992)
Density 1.08 (USCG, 1999)
EC Number 203-564-8
Flash Point 121° F (NTP, 1992)
Format liquid
Hazard Statements H226-H302-H314-H332
Applications Reagent||Solvent
MDL # MFCD00008705
Melting Point -99.6° F (NTP, 1992)
Molecular Formula C4H6O3
Molecular Weight 102.089 g/mol
Personal Protective Equipment Faceshields, full-face respirator, Gloves, Goggles, multi-purpose combination respirator cartridge, respirator filter
Physical Appearance Clear; Colorless Liquid
Product Families Description Acetic anhydride
Product Overview Acetic Anhydride
Refractive Index n20/D 1.390 (Lit.)
RTECS Number AK1925000
Safety Symbol GHS02, GHS05, GHS07
Solubility Soluble in cold (greater than or equal to 10mg/ml); Decomposes in hot (NTP, 1992)
Storage and Handling Store at Room Temperature (15-30 °C). Store Desiccated.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
Vapor Density 3.52 (NTP, 1992) (Relative to Air)
Vapor Pressure 10 mm Hg at 96.8° F (NTP, 1992)