Antipain inhibits trypsin, papain, and catherpsins A and B (a reversible inhibitor of cysteine and serine proteases). It is used to evaluate the role of proteases in cell transformations. It is used to help identify new proteases.
Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
Reversible inhibitor of serine/cysteine proteases
|Alternate Names||L-Valinamide; [(S)-1-Carboxy-2-phenylethyl]- carbamoyl-Arg-Val-Arg-al; [(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-arginyl-L-valyl-argininal; [(S)-1-Carboxy-phenethyl]-carbamoyl-Arg-Val-Arg-aldehyde|
|Application Notes||Antipain inhibits trypsin, papain, and catherpsins A and B (a reversible inhibitor of cysteine and serine proteases). It is used to evaluate the role of proteases in cell transformations. It is used to help identify new proteases.|
|Biochemical Physiological Actions||Reversible inhibitor of serine/cysteine proteases and some trypsin-like serine proteases. Its action resembles leupeptin; however, its plasmin inhibition is less and its cathepsin A inhibition is more than that observed with leupeptin. Chronic administration can reduce the frequency of chemically induced transformation in BALB/c-/3T3 cells.|
|Applications||Reversible inhibitor of serine/cysteine proteases|
|Molecular Formula||C27H44N10O6 (free acid)|
|Molecular Weight||677.629 g/mol|
|Personal Protective Equipment||Eyeshields, Gloves, respirator filter|
|Physical Appearance||Off-white Powder|
|Product Families Description||Antipain|
|Product Overview||Antipain Hydrochloride|
|Storage and Handling||Store at -20 °C. Store desiccated.|
|Typical Working Concentration||Effective concentration is 1 to 100 µM.|
|Usage Statement||Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.|