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Antipain Hydrochloride

Antipain Hydrochloride

Synonyms L-Valinamide; [(S)-1-Carboxy-2-phenylethyl]- carbamoyl-Arg-Val-Arg-al; [(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-arginyl-L-valyl-argininal; [(S)-1-Carboxy-phenethyl]-carbamoyl-Arg-Val-Arg-aldehyde

CAS Number: 37682-72-7 Molecular Formula: C27H44N10O6 (free acid) Molecular Weight: 677.629 g/mol

EC Number: 253-631-0

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SKU 02152843-CF
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Description

Product Description

Antipain Hydrochloride

Application Notes

Antipain inhibits trypsin, papain, and catherpsins A and B (a reversible inhibitor of cysteine and serine proteases). It is used to evaluate the role of proteases in cell transformations. It is used to help identify new proteases.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Reversible inhibitor of serine/cysteine proteases

Specifications
SKU 02152843-CF
Application Notes Antipain inhibits trypsin, papain, and catherpsins A and B (a reversible inhibitor of cysteine and serine proteases). It is used to evaluate the role of proteases in cell transformations. It is used to help identify new proteases.
Biochemical Physiological Actions Reversible inhibitor of serine/cysteine proteases and some trypsin-like serine proteases. Its action resembles leupeptin; however, its plasmin inhibition is less and its cathepsin A inhibition is more than that observed with leupeptin. Chronic administration can reduce the frequency of chemically induced transformation in BALB/c-/3T3 cells.
EC Number 253-631-0
Format powder
Hazard Statements H302
Applications Reversible inhibitor of serine/cysteine proteases
Molecular Formula C27H44N10O6 (free acid)
Molecular Weight 677.629 g/mol
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Physical Appearance Off-white Powder
Product Families Description Antipain
Product Overview Antipain Hydrochloride
RTECS Number YV9350700
Safety Symbol GHS07
Storage and Handling Store at -20 °C. Store desiccated.
Typical Working Concentration Effective concentration is 1 to 100 µM.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.