Dino

Lactoferrin

Lactoferrin

Packaging size: 50 mg

SKU 0215233350
Price:
$132.50
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Description

Product Description

Lactoferrin is an iron binding protein. It is structurally similar to transferrin, the plasma iron transport protein; but lactoferrin has a much higher affinity for iron (250 fold). It is very abundant in colostrum and small amounts can also be found in tears, saliva, mucous secretions and in the secondary granules of neutrophils. It is made by mucosal epithelium and neutrophils and is released by these cells in response to inflammatory stimuli. Bacterial growth is inhibited by its ability to sequester iron and also permeabilize bacterial cell walls by binding to lipopolysaccharides through its N-terminus. Lactoferrin can inhibit viral infection by binding tightly to the viral envelope protein. This prevents cell-virus fusion by blocking the binding domain. Lactoferrin appears to activate host defense systems in part by stimulating the release of interleukin-8, a neutrophil activator. It may also be involved in antibody and interleukin synthesis, lymphocyte proliferation and complement activation.

Application Notes

Lactoferrin exhibits antimicrobial activity against a variety of microorganisms and is also a useful cell culture growth factor that furnishes a source of iron to certain cell lines.

Key Applications

Cell culture applications | Antimicrobial Treatment

Specifications
SKU 0215233350
Application Notes Lactoferrin exhibits antimicrobial activity against a variety of microorganisms and is also a useful cell culture growth factor that furnishes a source of iron to certain cell lines.
Concentration Protein Content: ≥96%
Formulation Details Solid
Gene ID cow ... LTF(280846)
Applications Cell culture applications | Antimicrobial Treatment
Pack Size 50 mg
Physical Appearance Peach-colored Solid
Presentation Solid
Protein or Enzyme Type Growth Factors
Research Areas Growth Factors Receptors
Solubility Soluble in water 10 mg/mL.
Source Bovine Milk
Storage and Handling Store at +4°C.