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Prostaglandin I2 Sodium Salt

Prostaglandin I2 Sodium Salt

Synonyms PG-I2Na; Prostacycline; (5Z, 9α, 11α, 13E, 15S)-6,9α-epoxy-11α,15-dihydroxy-prosta-5,13-dien-1-oic acid, monosodium salt; Prostacyclin, sodium salt; Epoprostenol sodium salt; (5Z,9α,11α,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt

CAS Number: 61849-14-7 Molecular Formula: C20H31O5Na Molecular Weight: 374.453 g/mol

Beilstein Registry Number: 6472195 EC Number: 263-273-7 MDL Number: MFCD00135629

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SKU 02151969-CF
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Description

Product Description

Prostaglandin I2 Sodium Salt

Application Notes

Prostacyclin therapy improves hemodynamics in pulmonary arterial hypertension.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Potent inhibitor of platelet aggregation

Specifications
SKU 02151969-CF
Application Notes Prostacyclin therapy improves hemodynamics in pulmonary arterial hypertension.
Beilstein Registry Number 6472195
Biochemical Physiological Actions Prostaglandin I2 sodium salt stimulats platelet adenylyl cyclase. Nitric oxide is also produced in vascular endothelium where it inhibits platelet aggregation, regulates inducible cyclooxygenase production, and may work synergistically with prostacyclin to attenuate the thrombotic process. Prostacyclin is vasoprotective, protecting arterial walls from injury-induced lesions and cytoprotective in the liver and gastrointestinal tract.
EC Number 263-273-7
Format powder
Half Life Solutions of PGI2 at physiologic pH and room temperature will have a half-life from 1 to 12 minutes depending on buffer concentration. Half-life under physiological conditions is 2 minutes.
Hazard Statements H302-H312-H332
Applications Potent inhibitor of platelet aggregation
Molecular Formula C20H31O5Na
Molecular Weight 374.453 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Gloves
Physical Appearance White Powder
Product Families Description Prostaglandin I2
Product Overview Prostaglandin I2 Sodium Salt
Purity ≥99%
Safety Symbol GHS07
Storage and Handling Store at -20 °C. Store Desiccated.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.