Dino

D-Penicillamine

D-Penicillamine

Synonyms 3,3-Dimethyl-D-cysteine; 3-Mercapto-D-valine; D-(-)-2-Amino-3-mercapto-3-methylbutanoic acid

CAS Number: 52-67-5 Molecular Formula: C5H11NO2S Molecular Weight: 149.208 g/mol

Beilstein Registry Number: 1722375 EC Number: 200-148-8 MDL Number: MFCD00064302

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SKU 02151805-CF
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Description

Product Description

D-Penicillamine

Application Notes

It is used as an antirheumatic and as a chelating agent in Wilson's disease. It is used as a copper chelator to form mixed disulfides with cysteine or other sulfide media components. It is used to inactivate protein-1 DNA binding and to inhibit the growth of asynchronous cultures of rabbit articular chondrocytes.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Specifications
SKU 02151805-CF
Application Notes It is used as an antirheumatic and as a chelating agent in Wilson's disease. It is used as a copper chelator to form mixed disulfides with cysteine or other sulfide media components. It is used to inactivate protein-1 DNA binding and to inhibit the growth of asynchronous cultures of rabbit articular chondrocytes.
Beilstein Registry Number 1722375
Biochemical Physiological Actions Penicillamine is a characteristic degradation product of penicillin type antibiotics. One atom of copper combines with two molecules of penicillamine. Penicillamine reduces excess cystine excretion in cystinuria. This is by disulfide interchange between penicillamine and cystine, which results in formation of a readily excreted penicillamine-cysteine disulfide. Penicillamine interferes with the formation of cross-links between tropocollagen molecules and cleaves them when newly formed. Penicillamine lowers IgM rheumatoid factor and depresses T-cell activity.
EC Number 200-148-8
Format powder
Hazard Statements H315-H319-H335
Melting Point 198.5 °C
Molecular Formula C5H11NO2S
Molecular Weight 149.208 g/mol
Personal Protective Equipment dust mask, Eyeshields, Gloves
Physical Appearance White Powder
Product Families Description D-Penicillamine
Product Overview D-Penicillamine
Purity ≥99%
RTECS Number YV9425000
Safety Symbol GHS07
Solubility Water Solubility111000 mg/L (at 20 °C)
Storage and Handling +4°C
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.