Metformin Hydrochloride
Product Description
Metformin Hydrochloride
Application Notes
1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels. It may be used in the synthesis of the following:• bis(1,1-dimethylbiguanido)copper(II) octahydrate• bis(1,1-dimethylbiguanido)nickel(II)• 1,1-dimethylbiguanidium tetrabromothallate(III)
Usage Statement
Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications
An antidiabetic agent
| SKU | 02151691-CF |
| Application Notes | 1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels. It may be used in the synthesis of the following:• bis(1,1-dimethylbiguanido)copper(II) octahydrate• bis(1,1-dimethylbiguanido)nickel(II)• 1,1-dimethylbiguanidium tetrabromothallate(III) |
| Biochemical Physiological Actions | Metformin is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines. |
| EC Number | 214-230-6 |
| Format | White Crystalline Powder |
| Hazard Statements | H302-H315-H319 |
| Applications | An antidiabetic agent |
| Molecular Formula | C4H12ClN5 |
| Molecular Weight | 165.625 g/mol |
| Personal Protective Equipment | Dust mask, Eyeshields, Gloves |
| Physical Appearance | White Crystalline Powder |
| Product Families Description | Metformin hydrochloride |
| Product Overview | Metformin Hydrochloride |
| Purity | ≥98% |
| RTECS Number | DU1800000 |
| Safety Symbol | GHS07 |
| Solubility | In <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a>, 1.06X10+6 mg/L (miscible) at 25 deg C (est) |
| Storage and Handling | Store at Room Temperature (15-30 °C). Store Desiccated. |
| Usage Statement | Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Vapor Pressure | 7.58X10-5 mm Hg at 25 deg C (est) |