Metformin Hydrochloride

Metformin Hydrochloride

Synonyms N,N-Dimethylimidodicarbonimidic diamine; 1,1-Dimethylbiguanide hydrochloride; DMGG; LA-6023, Metformin

CAS Number: 1115-70-4 Molecular Formula: C4H12ClN5 Molecular Weight: 165.625 g/mol

EC Number: 214-230-6 MDL Number: MFCD00012582

Configure Your Product:

SKU 02151691-CF
Price:
$31.10
In Stock
Request a quote
Description

Product Description

Metformin Hydrochloride

Application Notes

1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels. It may be used in the synthesis of the following:• bis(1,1-dimethylbiguanido)copper(II) octahydrate• bis(1,1-dimethylbiguanido)nickel(II)• 1,1-dimethylbiguanidium tetrabromothallate(III)

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

An antidiabetic agent

Specifications
SKU 02151691-CF
Alternate Names N,N-Dimethylimidodicarbonimidic diamine; 1,1-Dimethylbiguanide hydrochloride; DMGG; LA-6023, Metformin
Application Notes 1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels. It may be used in the synthesis of the following:• bis(1,1-dimethylbiguanido)copper(II) octahydrate• bis(1,1-dimethylbiguanido)nickel(II)• 1,1-dimethylbiguanidium tetrabromothallate(III)
Biochemical Physiological Actions Metformin is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines.
EC Number 214-230-6
Format White Crystalline Powder
Hazard Statements H302-H315-H319
Applications An antidiabetic agent
MDL # MFCD00012582
Molecular Formula C4H12ClN5
Molecular Weight 165.625 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Gloves
Physical Appearance White Crystalline Powder
Product Families Description Metformin hydrochloride
Product Overview Metformin Hydrochloride
Purity ≥98%
RTECS Number DU1800000
Safety Symbol GHS07
Solubility In <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a>, 1.06X10+6 mg/L (miscible) at 25 deg C (est)
Storage and Handling Store at Room Temperature (15-30 °C). Store Desiccated.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Vapor Pressure 7.58X10-5 mm Hg at 25 deg C (est)