Hemocyanin

Hemocyanin

Synonyms KLH; Haemocyanin; Keyhole limpet hemocyanin

CAS Number: 9013-72-3

MDL Number: MFCD00131280

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SKU 02151233-CF
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$182.35
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Description

Product Description

Hemocyanin

Application Notes

Hemocyanin, Keyhole Limpet is used to immunize animals to elicit antibodies to small molecules (haptens) by covalent conjugation. It is often used as a carrier protein due to its highly immunogenic properties and the large number of lysine residues available for modification. Soluble KLH is suitable for the preparation of immunogens for injection, or as a control protein for ELISA and dot blot immunoassay due to its high solubility in water and buffers.Keyhole limpet hemocyanin (KLH) is a strong and well known immune-stimulant in both experimental animals and humans. It has been used as a hapten carrier protein to enhance antigen-specific T cell priming and is known to stimulate a CD4+ T-cell response. Hemocyanins stimulate Th1 reactions without known side effects, which make them ideal for long-term continuous treatment of cancer.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Preparation of immunogens

Specifications
SKU 02151233-CF
Alternate Names KLH; Haemocyanin; Keyhole limpet hemocyanin
Application Notes Hemocyanin, Keyhole Limpet is used to immunize animals to elicit antibodies to small molecules (haptens) by covalent conjugation. It is often used as a carrier protein due to its highly immunogenic properties and the large number of lysine residues available for modification. Soluble KLH is suitable for the preparation of immunogens for injection, or as a control protein for ELISA and dot blot immunoassay due to its high solubility in water and buffers.Keyhole limpet hemocyanin (KLH) is a strong and well known immune-stimulant in both experimental animals and humans. It has been used as a hapten carrier protein to enhance antigen-specific T cell priming and is known to stimulate a CD4+ T-cell response. Hemocyanins stimulate Th1 reactions without known side effects, which make them ideal for long-term continuous treatment of cancer.
Format lyophilized powder
Applications Preparation of immunogens
MDL # MFCD00131280
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
Physical Appearance Gray Lyophilized Powder
Product Families Description Hemocyanin
Product Overview Hemocyanin
Source Keyhole Limpet (Megathura crenulata)
Storage and Handling +4 °C
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.