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L-Glutamic Dehydrogenase

L-Glutamic Dehydrogenase

Synonyms L-GLDH; Glutamate dehydrogenase; L-Glutamate : NAD[P]+ oxidoreductase (deaminating); Glutamate Dehydrogenase from bovine liver

CAS Number: 2604152

EC Number: 232-848-4 MDL Number: MFCD00131461

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SKU 02151189-CF
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Description

Product Description

L-Glutamic Dehydrogenase

Application Notes

L-Glutamic Dehydrogenase(GLDH) can be measured in a medical laboratory to evaluate the liver function. Elevated blood serum GLDH levels indicate liver damage and GLDH plays an important role in the differential diagnosis of liver disease, especially in combination with aminotransferases. In clinical trials, GLDH can serve as a measurement for the safety of a drug.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Diagnosis of liver disease||Measurement for the safety of a drug

Specifications
SKU 02151189-CF
Application Notes L-Glutamic Dehydrogenase(GLDH) can be measured in a medical laboratory to evaluate the liver function. Elevated blood serum GLDH levels indicate liver damage and GLDH plays an important role in the differential diagnosis of liver disease, especially in combination with aminotransferases. In clinical trials, GLDH can serve as a measurement for the safety of a drug.
Biochemical Physiological Actions L-glutamic dehydrogenase catalyzes the conversion of glutamate to α-ketoglutarate.
EC Number 232-848-4
Format Suspension
Formulation Details Form: Suspension in 50% saturated ammonium sulfate; pH 7.6.
Hazard Statements H317
Applications Diagnosis of liver disease||Measurement for the safety of a drug
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
Physical Appearance Cloudy White Suspension
Product Families Description L-Glutamic Dehydrogenase
Product Overview L-Glutamic Dehydrogenase
Source Bovine Liver
Specific Activity ≥40 u/mg protein
Storage and Handling Store at +4 °C; do not freeze.
Typical Working Concentration For Continuous Spectrophotometric Rate Determination method: 0.3-0.6 unit/mL of L-Glutamic dehydrogenase in cold Triethanolamine buffer.
Unit Definition One unit will cause the transformation of 1.0 µmole of alpha-ketoglutarate per minute at pH 7.3 and 25 °C.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.