Daunomycin Hydrochloride

Daunomycin Hydrochloride

Synonyms Daunorubicin hydrochloride; Daunorubicine hydrochloride; Leukaemomycin C; (8S-cis)-8-Acetyl-10- [(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxyl]-7,8,9,10-tetrahydro- 6,8,11- trihydroxy-1- methoxy-5,12-naphthacenedione hydrochloride

CAS Number: 23541-50-6 Molecular Formula: C27H29NO10·HCl Molecular Weight: 563.984 g/mol

Beilstein Registry Number: 4229221 EC Number: 245-723-4 MDL Number: MFCD04974507

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SKU 02150777-CF
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Description

Product Description

Daunomycin Hydrochloride

Application Notes

Daunorubicin hydrochloride is used in photostability , antileukemic, and drug metabolism studies.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Photostability||Antileukemic||Drug metabolism studies

Specifications
SKU 02150777-CF
Alternate Names Daunorubicin hydrochloride; Daunorubicine hydrochloride; Leukaemomycin C; (8S-cis)-8-Acetyl-10- [(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxyl]-7,8,9,10-tetrahydro- 6,8,11- trihydroxy-1- methoxy-5,12-naphthacenedione hydrochloride
Application Notes Daunorubicin hydrochloride is used in photostability , antileukemic, and drug metabolism studies.
Beilstein Registry Number 4229221
Biochemical Physiological Actions Daunorubicin inhibits DNA and RNA synthesis as sequence specific ds-DNA intercalating agent. On binding to DNA, daunomycin intercalates, with its daunosamine residue directed toward the minor groove. Daunomycin effectively binds to every 3 base pairs which causes unwinding.
EC Number 245-723-4
Format powder
Hazard Statements H301-H334-H351
Applications Photostability||Antileukemic||Drug metabolism studies
MDL # MFCD04974507
Melting Point 370 to 374° F (decomposes) (NTP, 1992)
Molecular Formula C27H29NO10·HCl
Molecular Weight 563.984 g/mol
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator cartridge respirator filter
Physical Appearance Powder
Product Families Description Daunomycin hydrochloride
Product Overview Daunomycin Hydrochloride
RTECS Number HB7878000
Safety Symbol GHS06, GHS08
Solubility Soluble (NTP, 1992)
Source Streptomyces peucetius
Storage and Handling Store at +4 °C; protect from light.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.