Cytochalasin D

Cytochalasin D

Synonyms Zygosporin A; 3-Benzyl-3,3-alpha, 4, 5, 6, 6-alpha, 9, 10, 12, 15-Decahydro-6, 12, 15-Trihydroxy-4, 10, 12-Trimethyl-5-Methylene-1H-Cycloundec(d)isoindole-1, 11(2H) Dione, 15-Acetate

CAS Number: 22144-77-0 Molecular Formula: C30H37NO6 Molecular Weight: 507.627 g/mol

Beilstein Registry Number: 1632828 EC Number: 244-804-1 MDL Number: MFCD00077706

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SKU 02150771-CF
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Description

Product Description

Cytochalasin D

Application Notes

Cytochalasin D possesses antibiotic and antitumor activity. It also impairs maintenance of long term potentiation (LTP) of actin filaments. It is implicated in promoting conditions favorable for depolymerizing actin.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Potent inhibitor of actin polymerization

Specifications
SKU 02150771-CF
Alternate Names Zygosporin A; 3-Benzyl-3,3-alpha, 4, 5, 6, 6-alpha, 9, 10, 12, 15-Decahydro-6, 12, 15-Trihydroxy-4, 10, 12-Trimethyl-5-Methylene-1H-Cycloundec(d)isoindole-1, 11(2H) Dione, 15-Acetate
Application Notes Cytochalasin D possesses antibiotic and antitumor activity. It also impairs maintenance of long term potentiation (LTP) of actin filaments. It is implicated in promoting conditions favorable for depolymerizing actin.
Beilstein Registry Number 1632828
Biochemical Physiological Actions Disrupts actin microfilaments and activates the p53-dependent pathways causing arrest of the cell cycle at the G1-S transition. Inhibits smooth muscle contraction. Inhibits insulin-stimulated, but not basal, transport of glucose.
EC Number 244-804-1
Format powder
Hazard Statements H300-H361
Applications Potent inhibitor of actin polymerization
MDL # MFCD00077706
Melting Point 491 to 500° F (decomposes) (NTP, 1992)
Molecular Formula C30H37NO6
Molecular Weight 507.627 g/mol
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator filter, respirator cartridges
Physical Appearance White Powder
Product Families Description Cytochalasin D
Product Overview Cytochalasin D
RTECS Number GZ4850000
Safety Symbol GHS06, GHS08
Source Zygosporium mansoni
Storage and Handling Store at -20 °C; protect from light. Store Dessicated.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.