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Amikacin, PhytoPure™

Amikacin, PhytoPure™

Synonyms 1-N-[L(-)-4-Amino-2-hydroxy-butyryl] kanamycin A; O-3-Amino-3-deoxy-a -D-glucopyranosyl-(1 ---> 6)-O-6-amino-6-deoxy-a-D-glucopyranosyl-(1 ---> 4)]- N1 -(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-D-streptamine; Lukadin

CAS Number: 37517-28-5 Molecular Formula: C22H43N5O13 Molecular Weight: 585.60

Beilstein Registry Number: 1445422 EC Number: 253-538-5 MDL Number: MFCD11045969

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SKU 02150342-CF
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Description

Product Description

From Kanamycin A. An amino-glycoside antibiotic that works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. It is effective against gram-negative bacteria, fungi and mycobacteria.

Application Notes

Amikacin is most often used for treating infections with multidrug resistant Gram negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, and Enterobacter.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Antibiotic

Specifications
SKU 02150342-CF
Application Notes Amikacin is most often used for treating infections with multidrug resistant Gram negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, and Enterobacter.
Beilstein Registry Number 1445422
Biochemical Physiological Actions Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading. It interferes with the translocation of tRNA from the A-site to the P-site.
EC Number 253-538-5
Applications Antibiotic
Loss on Drying <9%
Melting Point 203-204 °C
Molecular Formula C<sub>22</sub>H<sub>43</sub>N<sub>5</sub>O<sub>13</sub>
Molecular Weight 585.60
Optical Rotation +100.5°
Personal Protective Equipment Eyeshields, Gloves,respirator filter
Physical Appearance White Powder
Potency ~900 µg/mg
Product Families Description Amikacin
Product Overview Amikacin
RTECS Number WK1955000
Solubility Water Solubility185000 mg/L (at 25 °C)
Storage and Handling Store at +4 °C.Store desssicated.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Vapor Pressure 5.79X10-28 mm Hg at 25 deg C (est)