5-Chloro-2′-Deoxyuridine

5-Chloro-2′-Deoxyuridine

Synonyms 5-Chlorodeoxyuridine; CLUDR

CAS Number: 50-90-8 Molecular Formula: C9H11ClN2O5 Molecular Weight: 262.646 g/mol

MDL Number: MFCD00006531

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SKU 02105478-CF
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Description

Product Description

5-Chloro-2′-Deoxyuridine

Application Notes

5-Chloro-2′-deoxyuridine (CldU) is used as a thymidine analogue to study the miscoding potential of hypochlorous acid damage to DNA and DNA precursors. When used with antibody based immunofluorescent imaging, 5-Chloro-2′-deoxyuridine incorporation may be used in protocols to identify sites of DNA replication. CldU may be used as a labeling substrate in conjunction with other halogenated uridine labeling substrates such as bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU).

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Biochemical||Analogue

Specifications
SKU 02105478-CF
Alternate Names 5-Chlorodeoxyuridine; CLUDR
Application Notes 5-Chloro-2′-deoxyuridine (CldU) is used as a thymidine analogue to study the miscoding potential of hypochlorous acid damage to DNA and DNA precursors. When used with antibody based immunofluorescent imaging, 5-Chloro-2′-deoxyuridine incorporation may be used in protocols to identify sites of DNA replication. CldU may be used as a labeling substrate in conjunction with other halogenated uridine labeling substrates such as bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU).
Hazard Statements H302-H312-H332-H351
Applications Biochemical||Analogue
MDL # MFCD00006531
Molecular Formula C9H11ClN2O5
Molecular Weight 262.646 g/mol
Personal Protective Equipment Dust mask , Eyeshields, Gloves
Physical Appearance White Powder
Product Families Description 5-Chloro-2'-deoxyuridine
Product Overview 5-Chloro-2′-Deoxyuridine
RTECS Number YU7400000
Safety Symbol GHS07, GHS08
Storage and Handling 0 °C
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
UV Visible Absorbance λ max (water): 276 ± 3 nm