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Coenzyme A Trihydrate

Coenzyme A Trihydrate

Synonyms CoA; CoASH; HSCo

CAS Number: 85-61-0 Molecular Formula: C21H36N7O16P3S·3H2O Molecular Weight: 767.533 g/mol

Beilstein Registry Number: 77809 EC Number: 201-619-0 MDL Number: MFCD06795839

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SKU 02104809-CF
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Description

Product Description

Coenzyme A Trihydrate

Application Notes

Coenzyme A facilitates removal of lipid peroxides by increasing mobilization of fatty acids, and promote repair of plasma membranes by activating phospholipid synthesis.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Enzymes||Inhibitors||Substrates

Specifications
SKU 02104809-CF
Application Notes Coenzyme A facilitates removal of lipid peroxides by increasing mobilization of fatty acids, and promote repair of plasma membranes by activating phospholipid synthesis.
Beilstein Registry Number 77809
Biochemical Physiological Actions The principal biologically active forms of pantothenic acid are coenzyme A (CoA) and acyl carrier protein (ACP). In CoA, the business center of the molecule is the pantothenic acid metabolite 4'-phosphopantetheine. Coenzyme A is comprised of 4'-phosphopantetheine linked by an anhydride bond to the nucloetide adenosine 5'-monophosphate. 4'-Phosphopantetheine itself is comprised of pantothenic acid linked at one end, via an amide bond, to beta-mercaptoethylamine, derived from L-cysteine, and at the other end to a phosphate group. The sulfhydryl group of 4'-phosphopantetheine, which is the business end of the coenzyme, forms thioesters with acyl groups producing acyl-CoA derivatives, including acetyl-CoA.Coenzyme A (CoA) is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP. CoA plays important roles in many metabolic pathways, including the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. One of the main functions of CoA is the carrying and transfer of acyl groups. Acylated deriviates, for example acetyl-CoA, are critical intermediates in many metabolic reactions. CoA levels can be altered during starvation, and in conditions such as cancer, diabetes, and alcoholism.
EC Number 201-619-0
Format Free Acid
Applications Enzymes||Inhibitors||Substrates
Molecular Formula C21H36N7O16P3S·3H2O
Molecular Weight 767.533 g/mol
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Physical Appearance White powder
Product Families Description Coenzyme A
Product Overview Coenzyme A Trihydrate
Storage and Handling -20 °C
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
UV Visible Absorbance λ max (water) 258 - 260 nm