Synonyms 8-MOP; 9-Methoxyfuro[3,2-g][1]benzopyran-7-one; Ammoidin; Methoxsalen; Xanthotoxin

CAS Number: 298-81-7 Molecular Formula: C12H8O4 Molecular Weight: 216.192 g/mol

Beilstein Registry Number: 196453 EC Number: 206-066-9 MDL Number: MFCD00005009

SKU 02103296-CF
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Product Description


Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

SKU 02103296-CF
Beilstein Registry Number 196453
Biochemical Physiological Actions 8-methoxypsoralen (8-MOP) plus ultraviolet A (UVA) irradiation induces monoadducts and interstrand cross-links in DNA and therefore can be used to study DNA repair and recombination mechanisms. Cultured normal human melanocytes treated with 8-methoxypsoralen and irradiated with ultraviolet A (UVA) formed 8-methoxypsoralen-phospholipid photoadducts that could be substituted for diacylglycerol to activate protein kinase C in a cell-free system. 8-MOP is an inactivator of purified reconstituted cytochrome P450. It also inhibits substance P-induced histamine release from substance P-activated rat peritoneal mast cells by suppressing the rise in [Ca2+].
EC Number 206-066-9
Extinction Coefficient EmM = 22.4 (249 nm), 11.5 (300 nm) (ethanol)(Lit.)
Format powder
Gene ID rat ... Maoa(29253)
Hazard Statements H302-H334
Melting Point 298° F (NTP, 1992)
Molecular Formula C12H8O4
Molecular Weight 216.192 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves
pH pH = 5.5
Physical Appearance White to Cream-colored Powder
Product Families Description 8-Methoxypsoralen
Product Overview 8-Methoxypsoralen
Purity ≥99%
RTECS Number LV1400000
Safety Symbol GHS07, GHS08
Solubility less than 1 mg/mL at 59° F (NTP, 1992)
Storage and Handling Store at Room Temperature (15-30 °C). Protect from light.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
Vapor Pressure 2.15X10-6 mm Hg at 25 deg C (est)