Vitamin B12
Product Description
Vitamin B12
Application Notes
Vitamin B12 plays a role in the synthesis of myelin. It is a cofactor for two enzymes, methionine synthase and L-methylmalonyl-CoA mutase. The compound is also used as an antipernicious anemia factor.
Usage Statement
Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications
Antipernicious anemia factor||Cofactor||Treatment of vitamin B12 deficiency; cyanide poisoning; and hereditary deficiency of transcobalamin II
| SKU | 02103271-CF |
| Alternate Names | Cyanocobalamin; α-(5,6-Dimethylbenzimidazolyl)cyanocobamide; CN-Cbl; Cyanocob(III)alamin |
| Application Notes | Vitamin B12 plays a role in the synthesis of myelin. It is a cofactor for two enzymes, methionine synthase and L-methylmalonyl-CoA mutase. The compound is also used as an antipernicious anemia factor. |
| Base Catalog Number | 103271 |
| Beilstein Registry Number | 4122889 |
| Biochemical Physiological Actions | Biosynthesis of the basic structure of the vitamin is accomplished only by bacteria(which usually produce hydroxocobalamin). Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine. |
| Boiling Point | > 300 deg C |
| CAS # | 68-19-9 |
| EC Number | 200-680-0 |
| Format | powder |
| Applications | Antipernicious anemia factor||Cofactor||Treatment of vitamin B12 deficiency; cyanide poisoning; and hereditary deficiency of transcobalamin II |
| Loss on Drying | ≤12% |
| Melting Point | > 300 °C |
| Molecular Formula | C63H88N14O14PCo |
| Molecular Weight | 1355.388 g/mol |
| Personal Protective Equipment | Eyeshields, Gloves, respirator filter |
| pH | Commercially available <a class="pubchem-internal-link multiple-CIDs" href="https://pubchem.ncbi.nlm.nih.gov/compound/cyanocobalamin">cyanocobalamin</a> for injection has a pH of 4.5-7 |
| Physical Appearance | Red Powder |
| Product Families Description | Vitamin B12 |
| Product Overview | Vitamin B12 |
| Purity | ≥96% |
| RTECS Number | GG3750000 |
| Solubility | <h5 class="minor-section-title">Water Solubility</h5>12500 mg/L |
| Storage and Handling | Store at +4 °C; desiccate. |
| Usage Statement | Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |