Uridine Anhydrous N/H

Uridine Anhydrous N/H

Synonyms 1-B-D-Ribofuranosyluracil; Uracil-1-β-D-ribofuranoside.

CAS Number: 58-96-8 Molecular Formula: C9H12N2O6 Molecular Weight: 244.2

Beilstein Registry Number: 754902 EC Number: 200-407-5 MDL Number: MFCD00006526

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SKU 02103216-CF
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Description

Product Description

Uridine is one of the four basic components of ribonucleic acid (RNA); the other three are adenosine, guanosine, and cytidine. Upon digestion of foods containing RNA, uridine is released from RNA and is absorbed intact in the gut. Uridine plays a role in the glycolysis pathway of galactose.

Application Notes

Antiviral and Antienzyme Activity – Baba et al., have shown in In Vitro studies that DSS inhibits the binding of various enveloped viruses including Human Immunodeficiency Virus (HIV), Herpes Virus (HSV) and Cytomegalovirus (CMV) to cells. Additionally, DSS has also shown to exhibit a potent inhibitory effect on many enzymes, for example hyaluronidase, adenylate cyclase, and amylase. Hofer at al., have shown that DSS induces bacterial translocation in HIV-infected humanized mice.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals

Key Applications

Metabolic Labelling

Specifications
SKU 02103216-CF
Alternate Names 1-B-D-Ribofuranosyluracil; Uracil-1-β-D-ribofuranoside.
Application Notes Antiviral and Antienzyme Activity – Baba et al., have shown in In Vitro studies that DSS inhibits the binding of various enveloped viruses including Human Immunodeficiency Virus (HIV), Herpes Virus (HSV) and Cytomegalovirus (CMV) to cells. Additionally, DSS has also shown to exhibit a potent inhibitory effect on many enzymes, for example hyaluronidase, adenylate cyclase, and amylase. Hofer at al., have shown that DSS induces bacterial translocation in HIV-infected humanized mice.
Beilstein Registry Number 754902
Chemical Class Biochemicals
EC Number 200-407-5
Grade Anhydrous
Applications Metabolic Labelling
MDL # MFCD00006526
Melting Point 160 - 171 °C
Molecular Formula C9H12N2O6
Molecular Weight 244.2
Personal Protective Equipment Eyeshields,Faceshields,Gloves,respirator filter
Physical Appearance White Powder
Purity ~99%
RTECS Number YR1450000
Solubility Soluble in 0.1 N HCl (50 mg/mL - clear, colorless solution).
Storage and Handling Room Temperature
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals
UV Visible Absorbance λ max (water) 260 - 263 nm