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Tris Hydrochloride

Tris Hydrochloride

Synonyms Trometamol; Tromethamine; Tris-[hydroxymethyl]aminomethane; 2-Amino-2-(hydroxymethyl)-1,3-propanediol

CAS Number: 1185-53-1 Molecular Formula: C4H11NO3·HCl Molecular Weight: 157.594 g/mol

Beilstein Registry Number: 3675235 EC Number: 214-684-5 MDL Number: MFCD00012590

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SKU 02103130-CF
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Description

Product Description

Tris Hydrochloride

Application Notes

Tris and Tris Hydrochloride have been useful as buffers in a wide variety of biological systems. Uses include pH control in vitro and in vivo for body fluids and in buffering systems for electrophoresis applications. Tris has been used as a starting material for polymers, oxazolones (with carboxylic acids) and oxazolidines (with aldehydes). It can be used for the direct standardization of a strong acid solution; the equivalence point can be determined either potentiometrically or by use of a suitable indicator such as 3-(4-Dimethylamino-1-naphthylazo)-4-methoxybenzenesulfonic acid .

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Biological buffer||Apoptosis

Specifications
SKU 02103130-CF
Application Notes Tris and Tris Hydrochloride have been useful as buffers in a wide variety of biological systems. Uses include pH control in vitro and in vivo for body fluids and in buffering systems for electrophoresis applications. Tris has been used as a starting material for polymers, oxazolones (with carboxylic acids) and oxazolidines (with aldehydes). It can be used for the direct standardization of a strong acid solution; the equivalence point can be determined either potentiometrically or by use of a suitable indicator such as 3-(4-Dimethylamino-1-naphthylazo)-4-methoxybenzenesulfonic acid .
Beilstein Registry Number 3675235
Biochemical Physiological Actions The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.
EC Number 214-684-5
Grade Reagent grade
Applications Biological buffer||Apoptosis
Molecular Formula C4H11NO3·HCl
Molecular Weight 157.594 g/mol
Personal Protective Equipment dust mask , Eyeshields, Gloves
Physical Appearance White Crystalline Powder
pKa 8.08 (25 °C)
Product Families Description TRIS hydrochloride
Product Overview Tris Hydrochloride
Purity >99%
Safety Symbol GHS07
Sterilization of Solutions Tris solutions can be autoclaved (121°C, 15 psi, 15 minutes) or sterile filtered.
Storage and Handling Room Temperature
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.