Poly-D-Lysine Hydrobromide
Product Description
Poly-D-Lysine Hydrobromide
Application Notes
It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding.Both the D- and L- form of the poly-lysine can be used as a coating substrate since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest poly-lysine. In this case, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine.
Usage Statement
Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
Key Applications
Cell adhesion
| SKU | 02102694-CF |
| Analysis Note | Molecular weight has been determined by Viscosity as well as by HPLC |
| Application Notes | It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding.Both the D- and L- form of the poly-lysine can be used as a coating substrate since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest poly-lysine. In this case, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine. |
| Biochemical Physiological Actions | This product is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. After absorption to the culture surface, poly-D-lysine increases the number of positively charged cell binding sites. |
| Applications | Cell adhesion |
| MDL # | MFCD00131934 |
| Personal Protective Equipment | Eyeshields, Gloves,respirator filter |
| Physical Appearance | White Powder |
| Product Families Description | Poly-D-lysine hydrobromide |
| Product Overview | Poly-D-Lysine Hydrobromide |
| Source | Synthetic |
| Storage and Handling | -20 °C; desiccate. |
| Usage Statement | Research Use Only (RUO). Ready for CE IVD labeling of clinical applications. |