Poly-D-Lysine Hydrobromide

Poly-D-Lysine Hydrobromide

CAS Number: 27964-99-4

MDL Number: MFCD00131934

Configure Your Product:

SKU 02102694-CF
Price:
$37.75
In Stock
Request a quote
Description

Product Description

Poly-D-Lysine Hydrobromide

Application Notes

It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding.Both the D- and L- form of the poly-lysine can be used as a coating substrate since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest poly-lysine. In this case, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Cell adhesion

Specifications
SKU 02102694-CF
Analysis Note Molecular weight has been determined by Viscosity as well as by HPLC
Application Notes It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding.Both the D- and L- form of the poly-lysine can be used as a coating substrate since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest poly-lysine. In this case, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine.
Biochemical Physiological Actions This product is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. After absorption to the culture surface, poly-D-lysine increases the number of positively charged cell binding sites.
Applications Cell adhesion
Personal Protective Equipment Eyeshields, Gloves,respirator filter
Physical Appearance White Powder
Product Families Description Poly-D-lysine hydrobromide
Product Overview Poly-D-Lysine Hydrobromide
Source Synthetic
Storage and Handling -20 °C; desiccate.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.