Dino

Pancreatin, U.S.P.

Pancreatin, U.S.P.

Synonyms Diastase vera; Pancreatin from hog pancreas

CAS Number: 8049-47-6

EC Number: 232-468-9 MDL Number: ≤ 5%

Configure Your Product:

SKU 02102557-CF
Price:
$44.50
In Stock
Request a quote
Description

Product Description

Pancreatin, U.S.P.

Application Notes

Pancreatin from porcine pancreas has been used:• for a study to assess the treatment of steatorrhea by lipase supplementation therapy• for a study to investigate treatment options for pancreatic diabetes in patients experiencing the decompensated stage of chronic pancreatitis• to safely and effectively remove formalin-fixed tissues from arterial grafts without causing structural damage and loss in fiber integrity• to assess cleavage by digestive enzymes.• for in vitro digestibility analysis and to test the sensitivities of cellulolytic bacteria inhibitors.• along with amyloglucosidase for the in vitro digestion of starch in food samples.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Metabolism

Specifications
SKU 02102557-CF
Analysis Note Contains many enzymes, including amylase, trypsin, lipase, ribonuclease and protease.
Application Notes Pancreatin from porcine pancreas has been used:• for a study to assess the treatment of steatorrhea by lipase supplementation therapy• for a study to investigate treatment options for pancreatic diabetes in patients experiencing the decompensated stage of chronic pancreatitis• to safely and effectively remove formalin-fixed tissues from arterial grafts without causing structural damage and loss in fiber integrity• to assess cleavage by digestive enzymes.• for in vitro digestibility analysis and to test the sensitivities of cellulolytic bacteria inhibitors.• along with amyloglucosidase for the in vitro digestion of starch in food samples.
Biochemical Physiological Actions Pancreatin contains enzymatic components including trypsin, amylase and lipase, ribonuclease, and protease, produced by the exocrine cells of the porcine pancreas. This combination of enzymes allows it to hydrolyze proteins, starch and fats. Pancreatin will convert not less than 25 times its weight of potato starch into soluble carbohydrates in 5 minutes in water at 40°C, will digest not less than 25 times its weight of casein in 60 minutes at pH 7.5 at 40°C and will release not less than microequivalents of acid per min per mg pancreatin from olive oil at pH 9.0 at 37°C.
EC Number 232-468-9
Foreign Activity Salmonella sp and E. coli
Format Absent
Gel Strength Stable Powder; proteolytic and diastatic activities are 1X N.F. Std.
Grade USP
Heavy Metals H315-H319-H334-H335
Applications Metabolism
Mean Pore Size MFCD00131789
Optical Rotation Fat * if each activity is > 3× the minimum -≤6.0% * if each activity is < 3× the minimum - ≥ 3.0%
Physical Appearance Off-White Powder
Preparation Method P261-P305 + P351 + P338-P342 + P311
Product Families Description Pancreatin
Product Overview Pancreatin, U.S.P.
RTECS Number RT9033000
Source Partly soluble in water; insoluble in alcohol.
Specific Activity Porcine Pancreas
Sterility Amylase Activity ≥ 25 USP u/mg Protease Activity ≥ 25 USP u/mg Lipase Activity ≥ 2.0 USP u/mg
Storage and Handling Store at -20 °C
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.