Glutathione Reduced

Glutathione Reduced

Synonyms γ-L-Glutamyl-L-cysteinyl-glycine; GSH

CAS Number: 70-18-8 Molecular Formula: H2NCH(CO2H)CH2CH2CONHCH(CH2SH)CONHCH2CO2H Molecular Weight: 307.321 g/mol

Beilstein Registry Number: 1729812 EC Number: 200-725-4 MDL Number: MFCD00065939

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SKU 02101814-CF
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Description

Product Description

Glutathione Reduced

Application Notes

Glutathione suppresses human immunodeficiency virus expression in chronically infected monocytic cells. It is a useful tripeptide involved in many aspects of metabolism, including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals

Key Applications

Protein purification||Elute GST-tagged protein from glutathione agarose

Specifications
SKU 02101814-CF
Alternate Names γ-L-Glutamyl-L-cysteinyl-glycine; GSH
Application Notes Glutathione suppresses human immunodeficiency virus expression in chronically infected monocytic cells. It is a useful tripeptide involved in many aspects of metabolism, including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds.
Beilstein Registry Number 1729812
Biochemical Physiological Actions Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.
EC Number 200-725-4
Applications Protein purification||Elute GST-tagged protein from glutathione agarose
MDL # MFCD00065939
Melting Point 195 °C
Molecular Formula H2NCH(CO2H)CH2CH2CONHCH(CH2SH)CONHCH2CO2H
Molecular Weight 307.321 g/mol
Optical Rotation -16 °(±) 5 ° (c=2, water)
Personal Protective Equipment Eyeshields,Gloves,respirator filter
Physical Appearance Off-white Powder
Product Families Description Glutathione reduced
Product Overview Glutathione Reduced
Purity ≥98%
RTECS Number MC0556000
Solubility 292.5 mg/mL
Storage and Handling +4 °C; store under nitrogen
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals