Folic Acid

Folic Acid

Synonyms Pteroylglutamic Acid; N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl] amino]benzoyl]-L-glutamic acid; N-[p-[[(2-amino-4-hydroxy-6-pteridinyl) methyl]amino] benzoyl] glutamic acid; N-(p-[(2-amino-4-hydroxypyrimido[4,5-b]pyrazin-6-yl) methylamino] benzoyl) glutamic acid; PGA; Liver Lactobacillus casei factor; Vitamin Bc; Vitamin M; Folsure; PteGlu

CAS Number: 59-30-3 Molecular Formula: C19H19N7O6 Molecular Weight: 441.404 g/mol

Beilstein Registry Number: 100781 EC Number: 200-419-0 MDL Number: MFCD00079305

Configure Your Product:

SKU 02101725-CF
Price:
$27.70
In Stock
Request a quote
Description

Product Description

Folic Acid

Application Notes

Folic acid (Vitamin B9 and folate) is essential to numerous bodily functions. The human body needs folate to synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in certain biological reactions. It is especially important in aiding rapid cell division and growth, such as in infancy and pregnancy.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Cofactors||Enzymes||Inhibitors and Substrates||Folic Acid Metabolism

Specifications
SKU 02101725-CF
Alternate Names Pteroylglutamic Acid; N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl] amino]benzoyl]-L-glutamic acid; N-[p-[[(2-amino-4-hydroxy-6-pteridinyl) methyl]amino] benzoyl] glutamic acid; N-(p-[(2-amino-4-hydroxypyrimido[4,5-b]pyrazin-6-yl) methylamino] benzoyl) glutamic acid; PGA; Liver Lactobacillus casei factor; Vitamin Bc; Vitamin M; Folsure; PteGlu
Application Notes Folic acid (Vitamin B9 and folate) is essential to numerous bodily functions. The human body needs folate to synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in certain biological reactions. It is especially important in aiding rapid cell division and growth, such as in infancy and pregnancy.
Beilstein Registry Number 100781
Biochemical Physiological Actions Folic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon’ transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics).
EC Number 200-419-0
Extinction Coefficient 9.12, 25.1, 26.9 (0.1 M NaOH)(Lit.)
Format powder
Applications Cofactors||Enzymes||Inhibitors and Substrates||Folic Acid Metabolism
Loss on Drying <8.5%
MDL # MFCD00079305
Melting Point 482° F (decomposes) (NTP, 1992)
Molecular Formula C19H19N7O6
Molecular Weight 441.404 g/mol
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
pH A suspension of 1 g of folic acid in 10 ml of <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a> has a pH of 4.0-4.8. Aq solutions prepared with <a class="pubchem-internal-link CID-516892" href="https://pubchem.ncbi.nlm.nih.gov/compound/sodium%20bicarbonate">sodium bicarbonate</a> have a pH between 6.5 and 6.8.
Physical Appearance Orange Powder
pKa 8.26 (Lit)
Product Families Description Folic acid
Product Overview Folic Acid
Purity >95.0%
Residue on Ignition <0.3%
RTECS Number LP5425000
Solubility Almost insoluble (NTP, 1992)
Storage and Handling Store at Room Temperature (15-30 °C). Protect from light.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
UV Visible Absorbance 256 ± 3 nm (0.1 N NaOH)
Vapor Pressure 6.2X10-20 mm Hg at 25 deg C /Estimated/