β-Estradiol

β-Estradiol

Synonyms 1,3,5(10)-Estratriene-3,17β-diol; 17β-Estradiol, 3,17β-Dihydroxy-1,3,5(10)-estratriene; Dihydrofolliculin; Altrad; Bardiol; Dihydrofollicular Hormone; Dihydrofolliculin; Dihydromenformon; Dihydrotheelin; 3,17-betaDihydroxyestra-1,3,5(10)-triene; Dihydroxyestrin; 3,17-beta-Dihydroxyoestra-1,3,5-triene; 3,17-beta-Dihydroxy-1,3,5(10)-oestratriene; Dihydroxyoestrin; Dimenformon; Dimenformon Prolongatum; Diogyn; Diogynets; E(sub 2); 3,17-Epidihydroxyestratriene; 3,17-Epidihydroxyoestratriene; Estradiol-17-beta; alpha-Estradiol; 3,17-beta-Estradiol; 17-beta-Estradiol; cis-Estradiol; D-Estradiol; D-3,17-beta-Estradiol; Estraldine; Estra-1,3,5(10)-Triene-3,17-betaDiol; Estrovite; Femestral; Femogen; Gynergon; Gynestrel; Ovahormon; Ovocycline; Primofol; Progynon; Diogyn; Estrace; Estraderm; Estroclim; Evorel; Gynoestryl; Macrodiol; Menorest; Oestrogel; Ovocylin; Profoliol B; Systen; Vagifem; Zumenon; cis-estradiol

CAS Number: 50-28-2 Molecular Formula: C18H24O2 Molecular Weight: 272.388 g/mol

Beilstein Registry Number: 1914275 EC Number: 200-023-8 MDL Number: MFCD00003693

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Description

Product Description

β-Estradiol

Application Notes

β-Estradiol is used to study cell differentiation and transformations (tumorigenicity). The pharmacology and HPLC determination of β-Estradiol in plasma and urine have been reported.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Potent mammalian estrogenic hormone

Specifications
SKU 02101656-CF
Alternate Names 1,3,5(10)-Estratriene-3,17β-diol; 17β-Estradiol, 3,17β-Dihydroxy-1,3,5(10)-estratriene; Dihydrofolliculin; Altrad; Bardiol; Dihydrofollicular Hormone; Dihydrofolliculin; Dihydromenformon; Dihydrotheelin; 3,17-betaDihydroxyestra-1,3,5(10)-triene; Dihydroxyestrin; 3,17-beta-Dihydroxyoestra-1,3,5-triene; 3,17-beta-Dihydroxy-1,3,5(10)-oestratriene; Dihydroxyoestrin; Dimenformon; Dimenformon Prolongatum; Diogyn; Diogynets; E(sub 2); 3,17-Epidihydroxyestratriene; 3,17-Epidihydroxyoestratriene; Estradiol-17-beta; alpha-Estradiol; 3,17-beta-Estradiol; 17-beta-Estradiol; cis-Estradiol; D-Estradiol; D-3,17-beta-Estradiol; Estraldine; Estra-1,3,5(10)-Triene-3,17-betaDiol; Estrovite; Femestral; Femogen; Gynergon; Gynestrel; Ovahormon; Ovocycline; Primofol; Progynon; Diogyn; Estrace; Estraderm; Estroclim; Evorel; Gynoestryl; Macrodiol; Menorest; Oestrogel; Ovocylin; Profoliol B; Systen; Vagifem; Zumenon; cis-estradiol
Application Notes β-Estradiol is used to study cell differentiation and transformations (tumorigenicity). The pharmacology and HPLC determination of β-Estradiol in plasma and urine have been reported.
Beilstein Registry Number 1914275
Biochemical Physiological Actions The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation.
EC Number 200-023-8
Extinction Coefficient EM(280 nm) = 1950(Lit.)
Format powder
Gene ID human ... ESR1(2099), ESR2(2100), ESRRA(2101), ESRRB(2103), GPER(2852), SERPINA6(866); mouse ... Esr1(13982), Esr2(13983), Esrra(26379); rat ... Afp(24177), Ar(24208), Esr1(24890), Esr2(25149), Shbg(24775)
Hazard Statements H351-H360Fd-H362
Applications Potent mammalian estrogenic hormone
MDL # MFCD00003693
Melting Point 151-152
Molecular Formula C18H24O2
Molecular Weight 272.388 g/mol
Optical Rotation +76° to +83° (c = 1% in dioxane at 25 °C)
Personal Protective Equipment Eyeshields, full-face particle respirator , Gloves, respirator cartridge , respirator filter,
Physical Appearance White Powder
Product Families Description β-Estradiol
Product Overview β-Estradiol
RTECS Number KG2975000
Safety Symbol GHS08
Solubility Water Solubility3.6 mg/L (at 27 °C)
Storage and Handling Store at Room Temperature (15-30 °C). Store Under Nitrogen.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Vapor Pressure 6.38X10-9 mm Hg at 25 deg C (est)