Phenazine Methosulfate
Product Description
Phenazine Methosulfate
Application Notes
Phenazine Methosulfate is used in tyrosine transaminase test and for enzymic determination of ethanol in blood by the colorimetric micromethod. Used with ascorbic acid to determine nitric oxide reductase activity. Since the reduced PMS is easily oxidized by oxygen, it is used in assays as an electron carrier between enzymes and oxygen, cytochrome c, indophenols, or tetrazolium salts. The reduced PMS is used as an electron donor to reduce cytochrome c or in photosynthetic experiments. Usage of PMS for detection of specific dehydrogenases has been reported.
Usage Statement
Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
Key Applications
Used in tyrosine transaminase test
| SKU | 02100955-CF |
| Alternate Names | 5-Methylphenazinium methyl sulfate; N-Methylphenazonium methyl sulfate; PMS |
| Application Notes | Phenazine Methosulfate is used in tyrosine transaminase test and for enzymic determination of ethanol in blood by the colorimetric micromethod. Used with ascorbic acid to determine nitric oxide reductase activity. Since the reduced PMS is easily oxidized by oxygen, it is used in assays as an electron carrier between enzymes and oxygen, cytochrome c, indophenols, or tetrazolium salts. The reduced PMS is used as an electron donor to reduce cytochrome c or in photosynthetic experiments. Usage of PMS for detection of specific dehydrogenases has been reported. |
| Beilstein Registry Number | 3898869 |
| Biochemical Physiological Actions | PMS is reduced by flavoproteins such as succinic dehydrogenase. PMS is reduced non-enzymatically by NADH and NADPH. PMS is also reduced by dithionite, sodium borohydride, ascorbic acid, reduced ubiquinones, and reduced vitamin K. PMS reacts with sulfhydryl groups including those of enzymes. |
| EC Number | 206-072-1 |
| Format | powder |
| Hazard Statements | H315-H319-H335 |
| Applications | Used in tyrosine transaminase test |
| MDL # | MFCD00011923 |
| Molecular Formula | C14H14N2O4S |
| Molecular Weight | 306.336 g/mol |
| Personal Protective Equipment | Dust mask, Eyeshields, Gloves |
| Physical Appearance | Dark; Golden Yellow Powder |
| Product Families Description | Phenazine methosulfate |
| Product Overview | Phenazine Methosulfate |
| RTECS Number | SG1645000 |
| Safety Symbol | GHS07 |
| Storage and Handling | Store at +4 °C. Protect from light. |
| Usage Statement | Research Use Only (RUO). Ready for CE IVD labeling of clinical applications. |
| UV Visible Absorbance | λ max (water) 384 - 388 nm |