Phenazine Methosulfate

Phenazine Methosulfate

Synonyms 5-Methylphenazinium methyl sulfate; N-Methylphenazonium methyl sulfate; PMS

CAS Number: 299-11-6 Molecular Formula: C14H14N2O4S Molecular Weight: 306.336 g/mol

Beilstein Registry Number: 3898869 EC Number: 206-072-1 MDL Number: MFCD00011923

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SKU 02100955-CF
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Description

Product Description

Phenazine Methosulfate

Application Notes

Phenazine Methosulfate is used in tyrosine transaminase test and for enzymic determination of ethanol in blood by the colorimetric micromethod. Used with ascorbic acid to determine nitric oxide reductase activity. Since the reduced PMS is easily oxidized by oxygen, it is used in assays as an electron carrier between enzymes and oxygen, cytochrome c, indophenols, or tetrazolium salts. The reduced PMS is used as an electron donor to reduce cytochrome c or in photosynthetic experiments. Usage of PMS for detection of specific dehydrogenases has been reported.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Used in tyrosine transaminase test

Specifications
SKU 02100955-CF
Alternate Names 5-Methylphenazinium methyl sulfate; N-Methylphenazonium methyl sulfate; PMS
Application Notes Phenazine Methosulfate is used in tyrosine transaminase test and for enzymic determination of ethanol in blood by the colorimetric micromethod. Used with ascorbic acid to determine nitric oxide reductase activity. Since the reduced PMS is easily oxidized by oxygen, it is used in assays as an electron carrier between enzymes and oxygen, cytochrome c, indophenols, or tetrazolium salts. The reduced PMS is used as an electron donor to reduce cytochrome c or in photosynthetic experiments. Usage of PMS for detection of specific dehydrogenases has been reported.
Beilstein Registry Number 3898869
Biochemical Physiological Actions PMS is reduced by flavoproteins such as succinic dehydrogenase. PMS is reduced non-enzymatically by NADH and NADPH. PMS is also reduced by dithionite, sodium borohydride, ascorbic acid, reduced ubiquinones, and reduced vitamin K. PMS reacts with sulfhydryl groups including those of enzymes.
EC Number 206-072-1
Format powder
Hazard Statements H315-H319-H335
Applications Used in tyrosine transaminase test
MDL # MFCD00011923
Molecular Formula C14H14N2O4S
Molecular Weight 306.336 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Gloves
Physical Appearance Dark; Golden Yellow Powder
Product Families Description Phenazine methosulfate
Product Overview Phenazine Methosulfate
RTECS Number SG1645000
Safety Symbol GHS07
Storage and Handling Store at +4 °C. Protect from light.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
UV Visible Absorbance λ max (water) 384 - 388 nm