Alcohol Dehydrogenase

Alcohol Dehydrogenase

Synonyms ADH; Alcohol : NAD+ oxidoreductase

CAS Number: 9031-72-5

EC Number: 232-870-4 MDL Number: MFCD00081305

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SKU 02100161-CF
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Description

Product Description

Alcohol Dehydrogenase

Application Notes

Alcohol dehydrogenase catalyzes the reaction: RCH2OH +NAD+ ↔ RCHO + NADH + H+ It facilitates the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+ to NADH). In biotransformation, alcohol dehydrogenases are often used for the synthesis of enantiomerically pure stereoisomers of chiral alcohols.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Catalysis breakdown of ethanol||Synthesis of enantiomerically pure stereoisomers of chiral alcohols

Specifications
SKU 02100161-CF
Alternate Names ADH; Alcohol : NAD+ oxidoreductase
Application Notes Alcohol dehydrogenase catalyzes the reaction: RCH2OH +NAD+ ↔ RCHO + NADH + H+ It facilitates the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+ to NADH). In biotransformation, alcohol dehydrogenases are often used for the synthesis of enantiomerically pure stereoisomers of chiral alcohols.
Biochemical Physiological Actions Yeast alcohol dehydrogenase (yADH) serves as an excellent model system for enzyme-catalyzed H transfer because unlike many other enzymes, the chemical step, oxidation of a primary alcohol to an aldehyde by NAD+, is rate-limiting with aromatic substrates.
EC Number 232-870-4
Extinction Coefficient E1%260= 12.6(lit.)
Format powder
Grade 2× Crystalline
Isoelectric Point 5.4(lit.)
Applications Catalysis breakdown of ethanol||Synthesis of enantiomerically pure stereoisomers of chiral alcohols
MDL # MFCD00081305
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Physical Appearance Off-White Flaky Powder
Product Families Description Alcohol Dehydrogenase
Product Overview Alcohol Dehydrogenase
Source Yeast
Specific Activity ≥300 u/mg protein
Specificity Yeast ADH which has a more narrow specificity than that of liver enzyme; accepts ethanol; is somewhat active on the straight chain primary alcohols; and acts to a very limited extent on certain secondary and branched chain alcohols. NADP does not serve as coenzyme.
Storage and Handling +4 °C
Unit Definition One unit will convert 1.0 µmole of NAD/min at 25°C.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.