Cytosine-Β-D-Arabinofuranoside Hydrochloride

Cytosine-Β-D-Arabinofuranoside Hydrochloride

Synonyms AraC; Arabinosylcytosine; 1-β-D-Arabinofuranosylcytosine; Cytabarine; Cytosine 1-(β-D-Arabino­furanosyl)­cytosine hydrochloride; Ara-C hydrochloride; Arabinocytidine hydrochloride; Arabinosylcytosine hydrochloride; Cytarabine hydrochloride; Cytosine arabinoside hydrochloride; Cylocide; Cytosar Hydrochloride; Iretin; Spongocytidine Hydrochloride

CAS Number: 69-74-9 Molecular Formula: C9H13N3O5 • HCl Molecular Weight: 279.677 g/mol

EC Number: 200-713-9 MDL Number: MFCD00012839

Configure Your Product:

SKU 02100071-CF
Price:
$50.80
In Stock
Request a quote
Description

Product Description

Cytosine-Β-D-Arabinofuranoside Hydrochloride

Application Notes

It is used as an antineoplastic and antiviral agent.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Selective inhibitor of DNA synthesis

Specifications
SKU 02100071-CF
Application Notes It is used as an antineoplastic and antiviral agent.
Biochemical Physiological Actions Ara-C is phosphorylated to Ara-CTP and is incorporatee into DNA. It inhibits DNA replication by forming cleavage complexes with topoisomerase I resulting in DNA fragmentation, and ultimately induces apoptosis via the PKC signaling pathway. Does not inhibit RNA synthesis. Anti-leukemia agent.
EC Number 200-713-9
Format powder
Hazard Statements H317-H319-H341-H361
Applications Selective inhibitor of DNA synthesis
Melting Point 356 to 360° F (NTP, 1992)
Molecular Formula C9H13N3O5 • HCl
Molecular Weight 279.677 g/mol
Physical Appearance White Powder
Product Families Description Cytosine-β-D-arabinofuranoside
Product Overview Cytosine-Β-D-Arabinofuranoside Hydrochloride
RTECS Number HA5500000
Safety Symbol GHS07, GHS08
Solubility >42 [ug/mL]
Storage and Handling Store at 2-8 °C.
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
UV Visible Absorbance λmax (water) 280 ± 6 nm
Vapor Pressure 8.74X10-12 mm Hg at 25 deg C (est)