Methionine/Choline diet has been used to study nonalcoholic steatohepatitis (NASH).
Nonalcoholic steatohepatitis (NASH) is common liver injury in which the histopathological abnormalities mimic those of alcoholic steatohepatitis. This disorder is most frequently associated with type 2 diabetes, hyperlipidemia, and rapid weight loss. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis, in which they proposed that CYP2E1 could also be a factor in the development of NASH. The mice used in this experiment were fed MP's plain Methionine/Choline and our control diet.