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Synonyms Cys-Ser-Cys-Ser-Ser-Leu-Met- Asp-Lys-Glu-Cys-Val-Tyr-Phe- Cys-His-Leu-Asp-Ile-Ile-Trp, ET-1

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Endothelin 1 has been used for coating wells in polystryene ELISA plates.

Product Description

Endothelin-1 is a 21-amino acid peptide from vascular endothelial cells of different mammalian species is one of the most potent vasoconstrictors. It exerts a wide variety of effects on both vascular and non-vascular (e.g. heart, lung, brain) tissues. Toxic peptides from a snake venom, the sarafotoxins, show structural and functional homology to Endothelin-1. It is among the most potent positively inotropic agents.

Biochem/physiol Actions

Potent agonist for ETA and ETB endothelin receptors. Induces the production of hypoxia-inducible factor 1α, and, thus, the production of VEGF.


Keywords Peptides for Cell Biology, Peptides and Proteins, GPCR Proteins, Inhibitors and Substrates, Cell Signaling and Neuroscience, Cell Biology, Cell Signaling Enzymes, Biochemicals and Reagents
Key Applications Coating wells in polystryene ELISA plates
Application Areas Molecular Biology
Product Type Biochemicals
Species Reactivity Crosses with: human, porcine, canine, rat, mouse, bovine

Price and Availability

SKU-Pack Size Availability Price (USD) Quantity
02153092.2 - 250 μg Loading... -
0215309201 - 250 μg Loading... -
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