02101003 MP BIOMEDICALS

BETAINE

Anhydrous, White Powder

Synonyms Lycine, Oxyneurine, (Carboxymethyl)trimethylammonium inner salt, Glycine betaine, 1-carboxy-N,N,N-trimethylmethanammonium inner salt

  • CAS Number 107-43-7
  • Molecular Formula C5H11NO2
  • Molecular Weight 117.1
  • Beilstein Registry Number 3537113
  • EC Number 203-490-6
  • MDL Number MFCD00012123
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Properties

Grade Anhydrous
Keywords Amino Acid, Biochemicals and Reagents, Cell Biology, Cholinesterase, butyryl, Cichorium intybus (Chicory), Core Bioreagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Hordeum vulgare (Barley), Metabolic Pathways, Metabolites and Cofactors on the Metabolic Pathways Chart, Metabolomics, Nutrition Research, Other Biochemical, Phytochemicals by Chemical Classification, Phytochemicals by Plant (Food/Spice/Herb), Research Essentials
Product Type Biochemicals
Melting Point 310 °C (Lit.)
Presentation White Powder

Description

Applications

Betaine is a reagent that is used in soldering, resin curing fluxes, and organic synthesis. Betaine has been studied in its role in protecting plants from environmental stress and in maintaining osmolarity in mammalian cells. Betaine has been reported to diminish the base pair composition dependence of DNA thermal melting transitions, with a concentration of 5.2 M betaine being the value at which AT and GC base pairs are equally stable and hence subsequently found application in the polymerase chain reaction (PCR). The usefulness of betaine in PCR has resulted from its ability to enhance DNA amplification by diminishing the formation of secondary structure in GC-rich DNA regions. A protocol for the production of long-chain cDNAs that uses betaine and trehalose has been published. The permanent positive charge on betaine makes it a target of study for mass spectrometry (MS) analysis by such methods as electrospray ionization (ESI) MS.


Product Description

Betaine is a quaternary amine found in bacteria and higher plants which acts as an osmoprotectant (able to restore and maintain osmotic balance in living cells) and enhances the freezing tolerance of of living organisms. This is probably due to its involvement in the protection of macrocomponents of plant cells, such as protein complexes and membranes, under stress conditions. Betaine is biosynthesized in living cells by a two-step oxidation method from choline. The primary enzyme involved in this biosynthesis is choline oxidase.


Biochem/physiol Actions

End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.


Price and Availability

SKU-Pack Size Availability Price (USD) Quantity
0210100350 - 50 g In Stock 26.60
0210100380 - 100 g In Stock 34.10
0210100391 - 1 kg In Stock 119.70
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